IndraLab

Statements

USP19 activates cell growth. 3 / 3
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"The results showed that knockdown of USP19 suppressed cell proliferation in SGC7901 cells while overexpressing USP19 accelerated cell growth in GES1 cells, as determined by MTT assay (P < 0.01, XREF_FIG and XREF_FIG)."
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"18 Genetic depletion of USP19 reduced Ewing sarcoma cell growth in vitro and in mice largely through destabilizing EWS–FLI1 proteins."
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"Therefore, the USP19 modulation of prostate cancer cell growth occurs through a regulation of cell cycle progression from G0/G1 to S phase and does not affect the rate of apoptotic cell death."
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