Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Cholesterol activates ATXN3. 1 / 1

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"ERAD is also essential for physiological processes by regulating the abundance of normal proteins of the ER, such as monooxygenase cytochrome p450; cholesterol metabolism regulatory proteins 3-hydroxy-3-methylglutaryl-CoA reductase, insulin induced gene-1 and apolipoprotein B; neurodegenerative disease proteins superoxide dismutase-1 and ataxin-3; and the metastasis suppressor KAI1 and CD82 XREF_BIBR XREF_BIBR XREF_BIBR XREF_BIBR XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...