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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP45 binds ERCC1-XPF. 2 / 2

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"USP45 interacts specifically with ERCC1-XPF via its N-terminal 61 residues."

25538220

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"Upon UV exposure, USP45 interacts with ERCC1-XPF but the USP45 mutant (Asp25Ala, Glu26Ala) that is catalytically active but that can not bind to ERCC1 failed to deubiquitinate ERCC1."

27827925

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...