IndraLab

Statements

reach
"We found that (i) USP14 could bind to AR, and additionally, both genetic and pharmacological inhibition of USP14 accelerated the ubiquitination and degradation of AR; (ii) downregulation or inhibition of USP14 suppressed cell proliferation and colony formation of LNcap cells and, conversely, overexpression of USP14 promoted the proliferation; and (iii) reduction or inhibition of USP14 induced G0/G1 phase arrest in LNcap prostate cancer cells."
28151478
reach
"The downregulation of USP14 significantly inhibited breast cancer cell proliferation and metastasis."
29326710
reach
"Knockdown of Ubiquitin Specific Protease 14 (USP14) Inhibits the Proliferation and Tumorigenesis in Esophageal Squamous Cell Carcinoma Cells."
27629392
reach
"Downregulation of USP14 significantly inhibited ESCC cell proliferation and ESCC tumor growth in nude mice."
27629392
reach
"Downregulation of USP14 Suppresses the Proliferation of ESCC Cells."
27629392
reach
"The results demonstrated that downregulation of USP14 significantly inhibited the proliferation in EC109 (XREF_FIG) and TE10 cells (XREF_FIG)."
27629392
reach
"We also found that downregulation of USP14 significantly inhibited ESCC cell proliferation and ESCC tumor growth in nude mice."
27629392
reach
"Knockdown of USP14 with the lentiviral vector delivery of shRNA in human hepatocarcinoma SMMC7721 cells suppressed cell proliferation, altered the cell cycle and induced cell apoptosis."
26397990
reach
"For example, Zhu et al. reported that expression of USP14 was increased in breast cancer tissues, and downregulation of USP14 significantly inhibited breast cancer cell proliferation and metastasis XREF_BIBR."
27629392
reach
"USP14 ablation reduces cancer cell proliferation in vitro and colorectal tumorigenesis in vivo by downregulating MAPK/JNK pathway activation."
36693850