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UCHL5 activates cell cycle. 3 / 3
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"Additionally, XAV939 treatment showed a smaller sub-G1 population when compared with the untreated group and prevented the cell cycle acceleration caused by UCHL5 overexpression (Figure 6D)."
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"As shown in Figure 3E , UCHL5 silent cells showed a remarkable increase in the sub-G1 population compared to negative control , indicating that UCHL5 deficiency induced cell cycle arrest ."
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"UCHL5 knockdown in LUAD cells significantly inhibited cell proliferation and reduced the expression of key cell cycle proteins."
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