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UCHL1 inhibits MDM2. 2 / 2

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"They also observed an increase in polyubiquitination and degradation of mdm2 in response to UCH-L1 over-expression, suggesting UCH-L1 suppresses mdm2 to stabilize p53 levels [XREF_BIBR]."

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"Thus , in breast cancer models , UCHL1 can induce the levels of p53 and reduce mdm2 protein levels ."

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UCHL1 inhibits MDM2. 2 / 2

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