IndraLab

Statements

USP14 inhibits G1 phase. 3 / 3
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"Additionally, both genetic and pharmacological inhibition of USP14 significantly suppressed cell proliferation in AR responsive breast cancer cells by blocking G 0 / G 1 to S phase transition and inducing apoptosis."
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"Inhibition of USP14 causes G 0 / G 1 arrest and apoptosis in breast cancer cells."
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"Furthermore, USP14 depletion caused cell cycle arrest in the G1 phase (Figure 3J) and a higher apoptotic rate compared to control Cal-27 and TU686 cells (Figure 3L,M)."
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