IndraLab

Statements

COPS6 activates FASN. 2 / 2

| 2

reach

"Since both EGF and CSN6 signaling pathways can promote FASN accumulation, it is reasonable to deduce that inhibiting EGF signaling by cetuximab treatment plus attenuating FASN activity by orlistat might synergistically suppress CSN6-high CRC growth."

37202390

➶

reach

"Together, our studies demonstrate that the role of EGF/CSN6 in increasing FASN accumulation and promoting CRC malignancy can be recapitulated in clinical samples."

37202390

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

COPS6 activates FASN. 2 / 2

INDRA sources:

Databases

Reading