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Statements

CYLD inhibits p38. 10 / 10
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"Thus, the present study showed that inhibition of p38 by CYLD leads to reduced expression of PAI-1 expression in lung and contributes substantially to ALI and increased mortality rate in lethal S. pne[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17723219
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"CYLD inhibits p38, causing increased vascular leakage and acute lung injury [ xref ]."
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"By interacting with TRAF2, CYLD prevents p38MAPK activation."
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"Taken together, these findings indicated that CYLD negatively regulates the activation of TAK1, p38, and AP-1."
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"CYLD inhibits p38 , causing increased vascular leakage and acute lung injury [ 82 ] ."
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"Thus, the present study showed that inhibition of p38 by CYLD leads to reduced expression of PAI-1 expression in lung and contributes substantially to ALI and increased mortality rate in lethal S. pne[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Thus, CYLD prevents excessive activation of TAK1 and p38, which results in reduced FOXP3 expression and Treg generation."
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"CYLD reduced activation of p65, JAK2, STAT3, and p38 MAPK as well as fibrin production in livers of Listeria infected WT mice."
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"Treatment with MPA also increases the transcription of ubiquitin carboxyl-terminal hydrolase CYLD (log2FC 0.12, padj = 0.04), which is known to suppress the NF-κB, p38MAPK and c-Jun N-terminal kinase (JNK) cascades."
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"CYLD Impairs Production of Cytokines, ROS, and NO and Reduces Activation of NF-kappaB, ERK1/2, and p38MAPK in Lm Infected BMDM."
26834734