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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP11 activates SPRTN. 2 / 2

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"Depletion of USP11 increased SPRTN auto-proteolysis and sensitized cells to DPC inducing agents leading to increased accumulation of DPCs."

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"We observed that USP11 depletion also promotes SPRTN auto-cleavage, and auto-proteolysis of SPRTN is exacerbated in the combined absence of USP11 and USP7."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...