IndraLab

Statements


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sparser
"Intriguingly, although overexpressed USP19 interacts with Derlin-1 and other ERAD machinery factors in the membrane, endogenous USP19 is mostly in the cytosol where it binds Hsp90."

sparser
"It was shown that USP19 can interact with Derlin-1 and overexpression of wild type USP19 can inhibit the degradation of a few model ERAD substrates."

sparser
"Accordingly, we detect neither interaction of endogenous USP19 with Derlin-1 nor significant effect on ERAD by USP19 depletion."

reach
"It was shown that USP19 can interact with Derlin-1 and overexpression of wild type USP19 can inhibit the degradation of a few model ERAD substrates."

No evidence text available