IndraLab

Statements

Chloroquine inhibits ITCH. 6 / 6
| 6
reach
"Loss of Bhlhb5 interneurons abolished the inhibition effect of menthol on chloroquine induced itch [XREF_BIBR] confirming that " counter-stimuli " sensed by Trp channels work through Bhlhb5 inhibitory interneurons to achieve itch inhibition."
26385480
reach
"Neuronal responses to chloroquine were prevented by inhibiting Gbetagamma subunit activity, suggesting that the G alphaq pathway is not necessary for chloroquine induced itch [XREF_BIBR]."
25558916
reach
"Inhibition of M/K v 7 Currents Contributes to Chloroquine Induced Itch in Mice."
32694980
reach
"We found that systemic administration of NAC or PBN significantly alleviated compound 48/80- and chloroquine induced acute itch in a dose dependent manner, attenuated dry skin induced chronic itch, and suppressed oxidative stress in the affected skin."
27783328
reach
"In GRPR knockout mice, scratching from histamine, SLIGRL and chloroquine induced itch was reduced [XREF_BIBR]."
23497684
reach
"Compared to wild-type (WT) mice, TNFR1-knockout (TNFR1-KO) and TNFR1/R2 double-KO (DKO), but not TNFR2-KO mice, exhibited reduced acute itch induced by compound 48/80 and chloroquine (CQ)."
28365861