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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UBE2D1 activates OTUB1. 2 / 3

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"Together, these E2 enzymes are in 2.7-fold molar excess over OTUB1 and have a combined concentration of nearly 10 times the EC 50 for UBCH5 stimulation of OTUB1 DUB activity (XREF_FIG)."

23955022

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"Taken together, our results suggest that OTUB1 should be stimulated by uncharged UBCH5 in cells, and that variations in the ratio of E2 to E2 ~ Ub could be involved in regulating OTUB1 isopeptidase activity."

23955022

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...