IndraLab

Statements

OTUD6B leads to the ubiquitination of IRF3. 3 / 3
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reach
"To investigate the type of ubiquitin chain that IRF3 OTUD6B cleaves, we analyzed the type(s) of IRF3 polyubiquitination mediated by OTUD6B."
37650650
reach
"Our results showed that overexpression of OTUD6B, and not defective OTUD6B-C57S, dramatically attenuated the ubiquitination levels of exogenously expressed IRF3, demonstrating that OTUD6B does reduce IRF3 ubiquitination levels and its deubiquitinase activity is critical (Fig. 5C)."
37650650
trips
"Zebrafish otud6b Negatively Regulates Antiviral Responses by Suppressing K63-Linked Ubiquitination of irf3 and irf7."
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