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DNA UCHL3 phosphorylation activates UCHL3. 1 / 1

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"Lastly , we provide evidence showing that DNA damage-induced UCHL3 phosphorylation ( which is dependent on UCHL3 catalytic activity , ATM kinase and downstream NHEJ factors ) promotes destabilization of UCHL3 , suggesting that UCHL3 may dissociate from Ku80 to allow Ku ubiquitylation and subsequent removal from DNA ."

30559450

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DNA UCHL3 phosphorylation activates UCHL3. 1 / 1

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