IndraLab

Statements

CALM1 binds Psn. 5 / 5
| 5
sparser
"Since Cam contains four EF-hand motifs, we reasoned that Psn may physically interact with Cam as well."
19730737
sparser
"Psn and Cam physically interact."
19730737
sparser
"To confirm that Psn and Cam genetically interact we generated a recombinant transgenic line, which carried both a wing margin-GAL4 driver ( cut-GAL4 ) as well as a UAS-wild type Psn transgene ( cut-Psn )."
19730737
sparser
"Given that Cam is known to play an important role in the regulation of intracellular calcium levels, we wanted to examine whether Psn and Cam physiologically interact to regulate internal calcium stores."
19730737
sparser
"Since Psn has been linked to calcium deregulation and Cam is an important player in intracellular calcium homeostasis we further investigated the genetic interaction between Psn and Cam in a cellular context relevant to AD."
19730737