IndraLab

Statements

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"Contrary to previous findings , our results indicated that the knockdown of USP24 increased HCC proliferation in vitro, while USP24 overexpression inhibited these processes in vitro and in vivo."
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"It was found that overexpression of USP24 inhibited the proliferation of HCC cells, as indicated by the decrease in both cell viability (Fig. 5C) and colony formation (Fig. 5D, E)."
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"Previous studies have demonstrated that USP24 inhibited proliferation and migration of HCC, and our findings also indicated that USP24 increased cell death in HCC cells (Supplementary Fig. 4A)."
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"The results of the EdU and Transwell assays showed that the addition of the miR-21-5p inhibitor significantly inhibited cell proliferation and migration, that USP24 overexpression could reverse the ef[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"USP24 silencing promotes HCC cell proliferation and migration in vitro."
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"Silencing USP24 increases the cancer formation by inhibiting cellular apoptosis and increasing cellular proliferation."
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"For instance, although USP24 inhibits the proliferation of tumor cells, it promotes the spread of metastases in other types of malignancies [4, 35]."
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"Collectively, these results suggested that the knockdown of USP24 promotes the proliferation and migration of HCC cells in vitro."
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