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USP21 deubiquitinates IGF2BP3. 2 / 2
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"Moreover, USP16 knockdown significantly decreased IGF2BP3 protein level and increased IGF2BP3 ubiquitination level, whereas no effect of IGF2BP3 was observed on USP16 protein expression ( Fig. 5 D and[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"USP16 also deubiquitinates proteins in oncogenic pathways, for example, IGF2BP3 in gallbladder cancer [48], whereas Ct-HBx inhibits the expression level of USP16 in hepatocellular carcinoma [40], revealing the intrinsic link to cancer development."