IndraLab

Statements



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"For instance, Mg 2+ and Ni 2+ potently block Eag channels but have little effect on the Elk channel Kv12.1, which is preferentially blocked by Zn 2+."

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"Mg 2+ slowed eag activation kinetics in a voltage dependent manner, with a larger effect after smaller depolarizing steps (XREF_FIG C)."

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"Eag channel pH sensitivity is attenuated by Mg 2+ but remains significant even up to 1 mM and therefore is still likely to exist in vivo."