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MTDH increases the amount of KCNK2. 3 / 3

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"AEG-1 knockdown dramatically decreased the mRNA and protein levels of TREK1, suggesting that TERK1 is regulated by HIF-1α."

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"Astrocyte elevated gene-1 (AEG-1) also induces TREK-1 expression in astrocytes during ischemia [114]."

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"Upregulation of AEG-1 increased expression of TREK-1 in astrocytes, and knockdown of AEG-1 dramatically decreased the mRNA and protein levels of TREK-1, which were restored by expression of shRNA-insensitive AEG-1."

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IndraLab

Statements

MTDH increases the amount of KCNK2. 3 / 3

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