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USP8 decreases the amount of COL4. 2 / 2
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"Both in Sec13 knockdown cells and in USP8/Sec13 double-knockdown cells, we did not detect collagen IV in the culture media ( Fig. 4 B), suggesting that USP8 restricts COPII-dependent collagen IV secre[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In this study, we show that USP8 deubiquitinates Sec31A, modulates COPII carrier formation, and restricts collagen IV secretion."
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