IndraLab

Statements

USP8 increases the amount of corticotropin. 2 / 2
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"Activating mutation in Ubiquitin-specific peptidase (USP8) is identified to enhance cell proliferation and adrenocorticotropic hormone (ACTH) secretion from corticotroph pituitary adenoma."
38862897
reach
"Almost half of ACTH-secreting pituitary tumors were reported to develop because of ubiquitin-specific peptidase 8 (USP8) somatic mutation (40), which leads to an increased USP8 deubiquitinating activity and triggers the release of adrenocorticotropic hormone (ACTH)."
35528020