IndraLab

Statements


KRAS-G12D increases the amount of KRAS-G12D. 3 / 3
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reach
"The propensity of Kras G12D HSCs to generate T-ALL led us to investigate the effects of Kras G12D expression in early T-lineage cells."

reach
"Oncogenic KRAS is a key driver of human lung adenocarcinoma, and early stage lung tumors can be modeled using LoxP-Stop-LoxP Kras G12D knock-in mice (Kras LSL-G12D/+) in which expression of Cre in lung epithelial cells leads to the expression of oncogenic Kras G12D 18,19."

reach
"Using the CCSP Cre mouse to specifically activate expression of the oncogenic Kras G12D in Club cells, we investigated the expression of Mig-6 in CCSP Cre Kras G12D -induced lung tumors."