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BRCC3 increases the amount of TAFAZZIN. 1 / 1
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"At the endogenous level of TAZ (no doxycycline treatment), BRCC3 KD raised the expression of Cyr61, while upon TAZS89A expression, both TAZ target genes are significantly upregulated (Figure 2a), thus confirming the result of the screen.TAZ activity is mainly regulated by post-translational modifications, which affect its protein stability and its cellular localization [2,41]."