IndraLab

Statements

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"Moreover, USP22 overexpression can promote EMT and TGF-beta expression, whereas depletion of USP22 can reverse EMT and reduce metastasis of lung adenocarcinomas."
27155333
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"Moreover, USP22 downregulation repressed cell proliferation, invasion and epithelial-mesenchymal transition (EMT) via inactivation of PI3K/Akt signaling pathway in osteosarcoma cells (28)."
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"In this study, we found that quercetin significantly inhibited the expression of USP22 and Snail1 in high glucose (HG)-induced renal tubular epithelial cells (TECs), and reversed the expression of EMT-related proteins and inhibited the overproduction of fibronectin (FN) and Collage Type IV (Collagen IV) induced by high glucose."
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"Downregulation of USP22 inhibited OS cell proliferation, invasion, and EMT in vitro."
27983930
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"Ablation of USP22 expression remarkably attenuates melanoma migration, invasion, and epithelial-mesenchymal transition in vitro and suppresses melanoma metastasis in vivo."
39135915
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"The results suggested that USP22 downregulation obviously suppressed the EMT process in OS cells."
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