IndraLab

Statements



sparser
"Observations in one study indicated that CAM-DR in MM cells was associated with increase in solubility and redistribution of c-FLIP L allowing its binding to and inhibiting death-inducing signaling complex (DISC) (which forms following CD95 ligation) and thus blocking apoptosis [ xref ]."

sparser
"For example, anticancer drug-induced H3K27 hypermethylation is associated with CAM-DR in MM cells [ xref ]."

sparser
"Finally, we showed that the interaction of Numbl with integrin β1 promotes the formation of CAM-DR in MM cells."

sparser
"In summary, Numbl plays a significant role in the formation of CAM-DR in MM cells."