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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

KCNMA1 inhibits TB. 2 / 2

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"The fact that SLO-1, a K + channel that affects synaptic transmission by making membrane potential more negative, can suppress M4 --> TB neuromuscular transmission, strongly suggests the involvement at this synapse, like others, of a plasma membrane voltage gated calcium channel."

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"We showed previously that SLO-1 inhibits transmission at the M4 --> TB muscle synapse, and we argue below that UNC-2 and UNC-36 inhibits transmission by activating SLO-1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...