IndraLab

Statements

P5091 inhibits Ubiquitin. 2 / 2
| 2
reach
"Moreover, P5091 inhibits USP7-, but not USP2- or USP8 mediated cleavage of poly K48 linked ubiquitin chains (visualized by the presence or absence of mono-ubiquitin) (XREF_SUPPLEMENTARY)."
22975377
reach
"Continuous treatment with the USP7 inhibitor P22077 or P5091 substantially reversed the accumulation of SUMOylated proteins in Rnf4 cells, presumably by stabilizing ubiquitin chains on those proteins to enable proteasomal targeting (Figure 3C)."
38530355