IndraLab

Statements

INS phosphorylates USP20. 4 / 4
| 4
reach
"In cancer cells, feeding-induced nutrient stress caused the accumulation of insulin and glucose, which stimulated mTORC1 to phosphorylate USP20."
36755301
reach
"They found that elevated postprandial blood glucose and insulin levels activate mTORC1 (mechanistic target of rapamycin complex 1), which stabilizes HMGCR (3-hydroxy-methylglutaryl coenzyme A reductase), phosphorylates USP20 (ubiquitin-specific peptidase 20), and upregulates cholesterol biosynthesis."
36382190
reach
"The postprandial increase in insulin and glucose activates mammalian target of rapamycin 1 to phosphorylate the deubiquitylase ubiquitin-specific peptidase 20 (USP20)."
39173829
reach
"Subsequently, the upregulation of postprandial glucose and insulin levels promotes the phosphorylation of USP20 (122)."
38322269