IndraLab

Statements

reach
"However, catechin did not affect the activation of IRF3.To investigate the consequence of the inhibition of IRF3 by EGCG, we determined the expression of IRF3-target genes such as IFNβ."
16890209
reach
"The results from our previous studies showed that resveratrol, (-)-epigallocatechin-3-gallate (EGCG), 6-shogaol, and isoliquiritigenin, which are well-known anti-inflammatory agents, inhibit IRF3 acti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22668719
reach
"EGCG inhibited the activation of IRF3 induced by TRIF as determined by IRF3 binding site (IFNβ PRDIII-I)-reporter gene assay while catechin did not ( Fig. 4 A )."
16890209
reach
"EGCG inhibited the activation of IRF3 induced by overexpression of TBK1 as determined by IRF3 binding site (IFNβ PRDIII-I) reporter gene assay ( Fig. 4 C)."
16890209
reach
"Our results showed that EGCG inhibited the activation of IRF3 induced by the transfection of TBK1 expression plasmid."
16890209
reach
"EGCG suppressed activation of IRF3 induced by LPS (TLR4 agonist) or poly[I:C] (TLR3 agonist) as determined by reporter gene assay using IFNβ promoter domain containing IRF3 binding site (IFNβ PRDIII-I[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16890209
reach
"Youn and colleagues [XREF_BIBR] reported that EGCG could inhibit LPS- or PolyI : C mediated activation of interferon regulatory factor 3."
22768975
reach
"Furthermore, EGCG has been reported to inhibit the activation of transcription factor, NF-kappaB (possibly through the suppression of IkappaB kinase) and IRF3 (via suppression of kinase activity of TBK1) XREF_BIBR - XREF_BIBR."
20877565