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Statements

MYSM1 binds TRIM21. 13 / 13
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sparser
"Consistently, our data indicated that MYSM1 binds to TRIM21 in a SWIRM-dependent manner."
39695708
sparser
"MYSM1 interacts with TRIM21 to maintain the stability of TRIM21 protein."
39695708
sparser
"As depicted in Fig.  xref B, it was revealed that the SWIRM domain, but not the SANT or MPN domains, was involved in the interaction between MYSM1 and TRIM21."
39695708
sparser
"These data indicated that MYSM1 binds to TRIM21 via the SWIRM domain and deubiquitinates TRIM21 in an MPN domain-dependent manner (Fig.  xref F)."
39695708
sparser
"MYSM1 binds to TRIM21 via the SWIRM domain and deubiquitinates TRIM21 in an MPN domain-dependent manner."
39695708
sparser
"To further clarify the domain required for MYSM1-TRIM21 interaction."
39695708
reach
"As depicted in Fig. 6B, it was revealed that the SWIRM domain, but not the SANT or MPN domains, was involved in the interaction between MYSM1 and TRIM21."
39695708
sparser
"Through a Co-IP combined LC-MS/MS analysis, we found that MYSM1 directly interacted with tripartite motif-containing protein 21 (TRIM21)."
39695708
reach
"Consistently, our data indicated that MYSM1 binds to TRIM21 in a SWIRM-dependent manner."
39695708
sparser
"We conducted preliminary validation of the LC-MS/MS results and found that the interaction between endogenous MYSM1 and TRIM21 was observed in DOX-treated cardiac tissues (Fig.  xref E) and HL-1 cells (Fig.  xref F)."
39695708
sparser
"These findings confirmed the existence of a direct interaction between MYSM1 and TRIM21."
39695708
reach
"We conducted preliminary validation of the LC-MS/MS results and found that the interaction between endogenous MYSM1 and TRIM21 was observed in DOX-treated cardiac tissues (Fig. 5E) and HL-1 cells (Fig. 5F)."
39695708
reach
"These findings confirmed the existence of a direct interaction between MYSM1 and TRIM21."
39695708