IndraLab

Statements


DAXX inhibits USP7. 2 / 2
| 2

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"In promyelocytic leukemia death domain-associated protein could inhibit activation of USP7, thereby favoring the nuclear localization of PTEN ( Song et al., 2008 )."

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"Strikingly, PML counteracts HAUSP function in regulating PTEN ubiquitinylation and nuclear localization via the adaptor protein DAXX, which inhibits HAUSP mediated deubiquitinylation of PTEN [18]."