IndraLab

Statements

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"Overexpression of OTULIN in a rat model of cerebral ischemia/reperfusion inhibits the activation of the NF‐κB signaling pathway, thereby improving microglial activation and neuroinflammation."
39169794
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"OTULIN can inhibit the NF-κB signaling pathway to suppress the inflammatory reaction via de-ubiquitination."
38561559
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"Increased OTULIN expression was required for EA to inhibit the NF-kappaB signalling pathway in focal cerebral ischaemia and reperfusion rats."
33836646
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"As both CYLD and OTULIN negatively regulate the NF-kappaB signalling cascade, the impact of these deubiquitinases in different LUBAC dependent signalling cascades may be context dependent."
28446710
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"To further investigate whether enhanced OTULIN was required for EA to inhibit the NF-kappaB signalling pathway, OTULIN, p-IkappaBalpha, IkappaBalpha, cytoplasm-p65 and nucleus-p65 proteins from brain tissues in the ischaemic penumbra of the cerebral cortex were detected 24h after reperfusion."
33836646