IndraLab

Statements

BCL2 inhibits ATXN3. 2 / 2
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"The BCL2 and BAX ratio was decreased in preataxic carriers compared to controls, suggesting that the mitochondrial mediated apoptotic pathway is altered in MJD."
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"Similarly, at the protein level, abundance of Bcl2 and Bcl2/Bax ratio has been found to be decreased in human neuronal SK-N-SH cells expressing expanded-polyQ ATXN3 compared with the parental cells [22]."
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