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USP25 inhibits lipopolysaccharide. 3 / 3

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"Together, these data suggest that USP25 restricts the LPS induced production of proinflammatory cytokines and promotes LPS induced production of type I IFNs in various cell types."

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"Besides, USP25 has been shown to suppress LPS-induced NF-κB and MAPK activation by stabilizing TRAF3 through K48 deubiquitination."

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"As expected, LPS/Nigericin‐induced oligomerization of ASC was significantly reduced by USP25 overexpression in NRPCs (Figure 5G)."

39985261

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IndraLab

Statements

USP25 inhibits lipopolysaccharide. 3 / 3

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