IndraLab

Statements


ESR1 increases the amount of USP19. 2 / 2
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"These results demonstrate that (i) E2 induces USP19 expression through nuclear ERalpha, (ii) increased USP19 mediated deubiquitinating activity represses myogenesis, and (iii) ERbeta inhibits ERalpha activated USP19 expression."

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"A mutant form of ERalpha that is constitutively localized in the nucleus increased USP19 expression and decreased MHC and tropomyosin expression in the presence of E2."