IndraLab

Statements

USP10 activates DNA Damage. 3 / 4
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"We identify 9 direct binding partners of p53 in the nuclear RNA interactome, including USP10, which deubiquitinates and activates p53 in response to DNA damage, and Sumo1, which can itself become covalently coupled to p53 to regulate its activity and subcellular localization (XREF_SUPPLEMENTARY) XREF_BIBR XREF_BIBR XREF_BIBR."
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"USP10 promotes CRC proliferation, oxaliplatin resistance, and DNA damage repair by stabilising XAB2."
40069750
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"Overall, these findings suggest that USP10 promotes cell proliferation, oxaliplatin resistance, and DNA damage repair in CRC by stabilising XAB2."
40069750