IndraLab

Statements


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"HCN4 encodes the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 and was previously associated with BrS."

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"Loss-of-function mutations in HCN4 have been associated with BrS but may be modulatory by acting to unmask BrS by reducing heart rate. xref "

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"In addition, BrS has also been associated with HCN4, which encodes the hyperpolarization-activated cyclic nucleotide-gated potassium channel 4."