IndraLab

Statements


USP11 deubiquitinates PML. 8 / 8
1 | 1 6

reach
"USP11 deubiquitinates and stabilizes PML, thereby counteracting the functions of PML ubiquitin ligases RNF4 and the KLHL20-Cul3 (Cullin 3) and Roc1 complex."

reach
"Remarkably, USP11 was able to antagonize RNF4- and Roc1-Cul3-KLHL20-mediated PML ubiquitination in 293T cells and GBM cell line U87 (XREF_SUPPLEMENTARY)."

reach
"Next, we determined whether USP11 could deubiquitinate PML in vitro."

trips
"USP11 deubiquitinates and stabilizes PML, thereby counteracting the functions of PML ubiquitin ligases RNF4 and the KLHL20-Cul3 (Cullin 3)-Roc1 complex."

reach
"By contrast, USP11 promotes deubiquitination and stabilization of PML [XREF_BIBR]."

reach
"USP11 deubiquitinates PML."

reach
"We demonstrated that USP11 deubiquitinates and stabilizes PML."