IndraLab

Statements

Filgotinib inhibits JAK1. 9 / 9
4 1 | 4
tas
No evidence text available
26351728
tas
No evidence text available
25369270
reach
"Filgotinib inhibited JAK1 mediated signalling similarly to other JAKinibs, but with less inhibition of JAK2 dependent and JAK3 dependent pathways, providing a mechanistic rationale for its apparently differentiated efficacy : safety profile."
33741556
reach
"Filgotinib is another selective inhibitor of JAK1."
32655703
reach
"Filgotinib (GLPG0634) is a selective inhibitor of Janus kinase 1 (JAK1) currently in development for the treatment of rheumatoid arthritis and Crohn 's disease."
25681059
reach
"Filgotinib inhibits JAK1 for longer duration, this is evident from its pharmacodynamic and pharmacokinetic studies."
| PMC
tas
No evidence text available
24417533
dgi
No evidence text available
tas
No evidence text available