IndraLab

Statements

TNFAIP3 inhibits IL1B. 2 / 2
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"Using acute and chronic HDMs-driven asthma models, Vroman et al. recently found that conditional deletion of Tnfaip3 gene in mouse myeloid cells promotes the secretion of Th17-inducing cytokines IL-1β, IL-6, and IL-23, thereby increasing Th17 cell numbers and exacerbating neutrophilic inflammation (18)."
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"The feedback regulator TNFAIP3 (A20) which negatively regulates TNF-alpha and IL-1beta signalling is up-regulated in two datasets and is down-regulated in one dataset."
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