IndraLab

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5beta-dihydrotestosterone decreases the amount of USP22. 1 / 1
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"To determine if loss of USP22 could impact ARSV expression, and represent a novel mechanism to target constitutively active AR, USP22 expression was depleted by shRNA (shUSP22-2), which resulted in significantly reduced protein expression of both AR-FL and AR-SVs in androgen deprived and DHT stimulated conditions (XREF_FIG)."