IndraLab

Statements


ADRM1 inhibits UCHL5. 2 / 7
| 2

reach
"We propose that RA190 targets hRpn13 and Uch37 through parallel mechanisms and at proteasomes, RA190 inactivated Uch37 can not disassemble hRpn13 bound ubiquitin chains."

reach
"Rpn13 can disrupt UCH37’s inhibitory dimeric structure and potentially its oligomerisation ."