IndraLab

Statements


ERK binds EGF and EGFR. 4 / 4
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"EGF binds the EGF receptor, resulting in ERK activation."

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"ChIP-Seq analysis of constitutive and EGF-induced genome-wide binding of EGFR and ERK kinase components reveals their colocalization with Pol2 complex."

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"After EGF stimulation, activated ErbB1 and ERK associated with the cytoskeleton to a greater extent than did total ErbB1 and total ERK."

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"Subsequent EGFR binding by EGF and heparin binding (HB)-EGF was associated with enhanced EGFR tyrosine kinase activity, prolonged ERK activation, and a significant increase in cyclooxygenase-2 (COX-2) expression compared with 18Co cells treated with EGF and HB-EGF alone."