IndraLab

Statements


EGF binds ERK and EGFR. 3 / 3
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"Subsequent EGFR binding by EGF and heparin binding (HB)-EGF was associated with enhanced EGFR tyrosine kinase activity, prolonged ERK activation, and a significant increase in cyclooxygenase-2 (COX-2) expression compared with 18Co cells treated with EGF and HB-EGF alone."

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"EGF binds the EGF receptor, resulting in ERK activation."

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"ChIP-Seq analysis of constitutive and EGF-induced genome-wide binding of EGFR and ERK kinase components reveals their colocalization with Pol2 complex."