IndraLab

Statements


KCNH1 activates VEGF. 3 / 4
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"To investigate whether Eag1 silencing was able to inhibit intracellular signal transduction of VEGF, we first detected the expression of VEGF in MG-63 cells at different time points after Ad5-Eag1shRNA treatment."

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"Eag channels also appear to impart a selective advantage for tumour cells in hypoxia by production of hypoxia inducible factor-1 (HIF-1) and thereby increasing vascular endothelial growth factor (VEGF) and increased vascularisation [XREF_BIBR]."

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"Eag1 Expression Promotes VEGF Secretion in Vitro -- Among the many factors influencing angiogenesis, VEGF appears to be predominant."