IndraLab
Statements
reach
"If CG8334 inhibits mitophagy in flies, similar to USP15 in human cells, suppression of CG8334 levels would allow residual Parkin in parkin RNAi flies to target damaged mitochondria for removal.Parkin regulates mitochondrial homeostasis also through pathways unrelated to MOM protein ubiquitination and mitophagy."