IndraLab

Statements

YTHDF2 binds OTUB1. 8 / 8
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sparser
"These results collectively supported that PRSS8 is a key effector of OTUB1-YTHDF2."
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sparser
"In this study, we find that PRSS8 expression is suppressed by the OTUB1–YTHDF2 axis."
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sparser
"We further show a decrease in PRSS8 underlies the proproliferation by OTUB1-YTHDF2."
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sparser
"OTUB1-YTHDF2 decreases PRSS8 mRNA level."
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sparser
"Next, we went on to explore the potential effector downstream of the OTUB1–YTHDF2 axis."
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sparser
"This work not only uncovers a mechanism for decreased PRSS8 expression in prostate cancer but also highlights PRSS8 as a key mediator of OTUB1-YTHDF2 function in prostate cancer ( xref F )."
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sparser
"These data identified that PRSS8 expression was repressed by the OTUB1–YTHDF2 axis."
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sparser
"PRSS8 mediates the effect of OTUB1-YTHDF2 on prostate cancer cell proliferation."
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