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USP30 inhibits E3_Ub_ligase. 2 / 2

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"Overexpression of USP30 prevents pexophagy during amino acid starvation, by counteracting the action of the peroxisomal E3 ubiquitin ligase PEX2 XREF_BIBR, XREF_BIBR."

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"However, USP30 inhibits the E3 function of Parkin by removing K6-linked ubiquitin chains in mitochondria ( Bingol et al., 2014 ; Sato et al., 2017 )."

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IndraLab

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USP30 inhibits E3_Ub_ligase. 2 / 2

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