IndraLab

Statements

USP44 deubiquitinates Histone_H2B. 8 / 8
| 8
reach
"Our results indicate that both the deubiquitination of histone H2B by USP44 and deacetylation of histone H3 by HDAC3 contribute to N-CoR mediated transcriptional repression (XREF_FIG)."
27880911
reach
"29 , 30 Of note, USP44 deubiquitinates histone H2B both in vivo and in vitro, which contributes to N‐CoR (USP44 is a part of the N‐CoR complex)‐mediated repression of target genes."
32394588
reach
"However, whether USP44 directly deubiquitinates histone H2B or how its activity is targeted to chromatin is not known."
27880911
reach
"As part of N-CoR, USP44 deubiquitinates H2B both in vivo and in vitro, and it contributes to N-CoR-mediated repression of target genes, including a genome integrated luciferase reporter (Vaquero et al[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27880911
reach
"USP44 within N-CoR deubiquitinates H2B in vitro and in vivo, and ablation of USP44 impairs the repressive activity of the N and CoR complex."
27880911
reach
"However, whether USP44 directly deubiquitinates histone H2B or how its activity is targeted to chromatin are not known."
27880911
reach
"USP44 negatively regulates H2B ubiquitination during embryonic stem cell development [XREF_BIBR]."
23845989
reach
"Our results indicate that both the deubiquitination of histone H2B by USP44 and deacetylation of histone H3 by HDAC3 contribute to N-CoR-mediated transcriptional repression."
27880911