IndraLab

Statements

USP44 deubiquitinates Histone_H2B. 8 / 8
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"Additionally, USP44 deubiquitinates H2B, which is essential for ESC differentiation [70] ."
29864528
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"Our results indicate that both the deubiquitination of histone H2B by USP44 and deacetylation of histone H3 by HDAC3 contribute to N-CoR mediated transcriptional repression (XREF_FIG)."
27880911
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"Monoubiquitination of H2B can be restored by the inhibition of the deubiquitinases USP12, USP44 and USP7 [115]."
38201233
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"USP44 within N-CoR deubiquitinates H2B in vitro and in vivo, and ablation of USP44 impairs the repressive activity of the N and CoR complex."
27880911
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"USP44 negatively regulates H2B ubiquitination during embryonic stem cell development [XREF_BIBR]."
23845989
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"Ubiquitination by TBLR1 (6) could commit activators for degradation, or H2B deubiquitination by USP44 might figure in repression of ANGPTL4 by NCOR/SMRT (36)."
31428774
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"29 , 30 Of note, USP44 deubiquitinates histone H2B both in vivo and in vitro, which contributes to N‐CoR (USP44 is a part of the N‐CoR complex)‐mediated repression of target genes."
32394588
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"However, whether USP44 directly deubiquitinates histone H2B or how its activity is targeted to chromatin are not known."
27880911