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Modified UCHL1 decreases the amount of APP. 2 / 2

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"Furthermore, viral expression of UCHL1 significantly lowered the APP level (p < 0.05) (XREF_FIG), and partial loss of UCHL1 markedly increased the APP level in APP23 and gad mice (p < 0.05) (XREF_FIG)."

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"Overexpression of UCHL1 significantly reduced APP CTF production (p < 0.01) (XREF_FIG) and markedly lowered Abeta level in the hippocampi of the UCHL1 overexpressing mice 10 weeks after injection (p < 0.05) (XREF_FIG)."

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IndraLab

Statements

Modified UCHL1 decreases the amount of APP. 2 / 2

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