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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified UCHL1 decreases the amount of APP. 2 / 2

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"Furthermore, viral expression of UCHL1 significantly lowered the APP level (p < 0.05) (XREF_FIG), and partial loss of UCHL1 markedly increased the APP level in APP23 and gad mice (p < 0.05) (XREF_FIG)."

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"Overexpression of UCHL1 significantly reduced APP CTF production (p < 0.01) (XREF_FIG) and markedly lowered Abeta level in the hippocampi of the UCHL1 overexpressing mice 10 weeks after injection (p < 0.05) (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...